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Advancing Drug Development Through Network Medicine

November 5th 2026
Rare Diseases: AOP Health and LBI-NetMed Partner to Take Drug Development to the Next Level Through Network Data Science
  • AOP Health and LBI-NetMed combine expertise in rare diseases, drug development and computational biology.

  • The partnership aims to generate deeper insights into potential drug candidates and future therapeutic opportunities.

  • The collaboration supports faster, evidence-based development of urgently needed therapies for people living with rare diseases.

Vienna, 05.11.2026. The Austrian pharmaceutical company AOP Health and the Ludwig Boltzmann Institute for Network Medicine at the University of Vienna (LBI-NetMed) have launched a strategic scientific partnership to accelerate drug development. By combining AOP Health's expertise in rare diseases and pharmaceutical development with LBI-NetMed's capabilities in computational biology and network medicine, the partners aim to deepen the understanding of disease mechanisms. These insights can help identify promising therapeutic opportunities and support faster, evidence-based development decisions. The collaboration has already started with a joint pilot project and is designed as a long-term academic-industry partnership.

Increasingly, medicine is moving away from viewing diseases as the result of a single faulty gene or protein and towards understanding them as the consequence of complex interactions across entire biological systems. This network-based perspective is helping researchers uncover how disturbances across interconnected pathways drive disease and why understanding these interactions is essential for developing new therapies.

Translating Research into Application

To gain these insights, LBI-NetMed develops and applies advanced computational approaches that can map, visualize and analyze biological networks, with a particular focus on protein interactions.

To date, these approaches have largely been used in basic research settings. The collaboration with AOP Health creates an opportunity to further advance these methods and translate them into drug-development and clinical research activities.

Dr. Jörg Menche

This partnership enables us to bring our technology from research into practical application. Working with AOP Health allows us to demonstrate how our network-driven methodologies can support innovation and contribute to better outcomes for people living with rare diseases.

Supporting Smarter Development Decisions

For AOP Health, the partnership opens new opportunities to integrate network-based approaches into drug development. The joint platform enables researchers to investigate how drug candidates influence biological networks while also supporting the identification and prioritization of promising therapeutic targets. By combining computational insights with pharmaceutical development expertise, the collaboration aims to strengthen decision-making throughout the development process.
 

Zoltan Magyarics, MD PhD

LBI-NetMed’s specialized expertise in computational biology and network science adds a valuable new dimension to our development capabilities. By helping us gain deeper insights into disease mechanisms and potential therapies, the partnership supports the identification of new indications, better- informed decision-making in development programs and has the potential to accelerate the delivery of urgently needed treatments for patients with rare diseases.

Launching the Joint Pilot

The collaboration has already moved into active scientific work. The first joint pilot project focuses on one of AOP Health's development assets and will explore how advanced computational approaches can complement existing drug development activities. Both organizations view the pilot as the first step in a longer-term collaboration aimed at turning scientific insights into practical value for patients.

AOP Health and LBI-NetMed's new partnership:
By combining AOP Health's expertise in rare diseases and pharmaceutical development with LBI-NetMed's capabilities in computational biology and network medicine, the partners aim to deepen the understanding of disease mechanisms. 


Key Takeaways

What is the purpose of the partnership between AOP Health and LBI-NetMed?
AOP Health and LBI-NetMed have established a strategic scientific partnership to advance drug development for rare diseases. Combining pharmaceutical expertise with computational biology and network medicine, the collaboration aims to generate new therapeutic insights and support evidence-based development decisions.

How can computational biology support drug development for rare diseases?
Computational biology uses data analysis and advanced computer modelling to understand complex biological systems. In this collaboration, it helps researchers analyse biological networks, particularly protein interactions, to better understand diseases, identify potential therapeutic targets and evaluate drug candidates more effectively.

Why is network medicine important for developing new therapies?
Network medicine views diseases as the result of complex interactions across biological systems rather than isolated defects in a single gene or protein. This approach can reveal previously hidden disease mechanisms, helping researchers discover new therapeutic opportunities and improve the development of innovative treatments for people living with rare diseases.

What will AOP Health and LBI-NetMed work on together?
The partners have already launched a joint pilot project focused on one of AOP Health's development assets. The project will explore how computational and network-based approaches can complement existing drug development activities and support faster, more informed research and development decisions.

About LBI-NetMed

The Ludwig Boltzmann Institute for Network Medicine at the University of Vienna (LBI-NetMed) is a computational, data-driven institute dedicated to establishing a network-based understanding of human health across biological scales and translating these insights into medical and societal impact. https://netmed.lbg.ac.at

About AOP Health

AOP Health Group is a global pharmaceutical enterprise with headquarters in Vienna. Its mission is to address high unmet medical needs through impactful, science-driven therapies and care models. Since 1996, AOP Health has pioneered research where limited therapies exist, to develop solutions for patients with rare diseases and severe conditions in niche therapeutic areas. Guided by the principle "Needs. Science. Trust.” the AOP Health Group demonstrates its strong commitment to patients and healthcare professionals through innovation and long-term partnerships, to improve patient outcomes worldwide.

Press Contact.

Mag. Nina Roth, MAS

Head of Corporate Communications
nina.roth[at]aop-health.com

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