World Sepsis Day: Understanding symptoms better
Vienna, September 8, 2023. Sepsis is one of the most common causes of death around the world. Around 2 million people in Europe suffer from this disease each year – 28,000 of them in Austria. The condition proves fatal for around 7,500 people across Austria. By comparison, 4,293 people died of a heart attack in Austria last year. But what makes sepsis so dangerous?
Understanding sepsis better
The answer is simple: Being unaware. Because sepsis is a lurking threat primarily affecting people with a weak immune system and intensive care patients. But older people roughly over the age of 60 and infants under the age of one can also be affected. Cancer patients, diabetics or the chronically ill, as well as alcoholics and drug addicts also display an increased risk of sepsis.
AOP Orphan Pharmaceuticals GmbH (AOP Health) feels obliged to face up to this challenge because the company has been involved in research and development on therapies for intensive care patients for 25 years. Dr. Hugo Leodolter, Head of Medical Affairs Austria at AOP Health, a pharmaceutical company focused on rare diseases and intensive care medicine, explains:
“Sepsis does not have to be preceded by a major injury, but can also be the result of more or less everyday infections. This is why information is so important when it comes to increasing awareness and getting people to go to the doctor or the hospital at an early stage if they have a suspected infection and symptoms of sepsis appear.”
Photocredit: Studio Koekart, Natascha Unkart & Isabelle Köhler
How to recognize potential sepsis?
Septic patients often have a fever combined with severe chills, especially in the early stage. In contrast there are also cases of septicemia where affected patients have a low temperature (hypothermia). Rapid breathing and shortness of breath can also be symptoms of gradual sepsis, similarly to an increased heart rate or signs of infection, such as rashes, swellings, nausea, vomiting or hyperthermia, along with confusion or disorientation.
“A generally severe impairment and deterioration of the state of health is regarded as a general indication of sepsis. This means fast action is needed. Because in the event of severe sepsis, septic shock or late diagnosis the body is unable to maintain organ functions and the organs may fail. In other words, regardless of the infection site, the body can no longer handle the normal function of the organs. The result is that vital functions begin to shut down”, says Leodolter.
What is sepsis?
Sepsis means a life-threatening organ failure caused by patients’ dysregulated immune response to an infection. Triggers may include bacteria, viruses and fungi which infect areas of the body and spread rapidly throughout the whole body. Examples of causes include wounds, urinary tract infections through to pneumonia or even a mild case of the flu.
Every hour counts
Sepsis is an emergency where every hour counts. Anyone with a suspected infection and displaying at least one symptom of sepsis should visit a hospital immediately. The earlier the patient is treated, the greater the chances of survival.
 20% of all deaths are caused by sepsis, WHO in ÖGARI [Austrian Society for Anaesthesiology, Rescuscitation and Intensive Care Medicine]: https://www.oegari.at/web_files/cms_daten/gari_pressemitteilung_welt-sepsis-tag_am_13._september_2020.pdf
 Uni Innsbruck: https://www.i-med.ac.at/mypoint/news/730395.html#:~:text=In%20Europa%20erkrankt%20jährlich%20etwa,pro%20Jahr%2C%207.500%20sterben%20daran.
 Statistics Austria, Causes of Death 2022
About AOP Health
The AOP Health Group incorporates several companies including AOP Orphan Pharmaceuticals GmbH with its seat in Vienna, Austria (“AOP Health”). The AOP Health Group is the European pioneer for integrated therapies for rare diseases and in critical care. Over the past 25 years, the AOP Health Group has become an established provider of integrated therapy solutions operating from its headquarters in Vienna, its subsidiaries and representative offices throughout Europe and the Middle East, as well as through partners worldwide. The claim “Needs. Science. Trust.” sums up the foundation of the Group’s success: establishing trust through a continually high level of investment in research and development and a highly consistent and pragmatic orientation towards the needs of all stakeholders – especially the patients and their families as well as the healthcare professionals treating them.
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