AOP Health's Rapiblyk® (landiolol) Now Accessible via Vizient® Contract

Wilmington, February 5, 2026. AOP Health US, LLC announced today that Rapiblyk® (landiolol) is now more widely available across the United States through contract with Vizient®, the nation’s largest provider-driven healthcare performance improvement company. Hospitals and health systems nationwide now have increased access through the Vizient catalog to Rapiblyk®, enhancing flexibility while expanding the availability of this critical care therapy. 

Furthermore, through the Vizient contract, participating hospital clients may have enhanced access to tiered pricing and streamlined ordering.

AOP Health US previously announced the U.S. commercial availability of Rapiblyk® (landiolol), an ultra-short-acting, selective beta-1 adrenergic receptor blocker approved by the U.S. Food and Drug Administration (FDA) for the short-term reduction of ventricular rate in adults with supraventricular tachycardia (SVT) or irregular rapid heart rate, including atrial fibrillation and atrial flutter, in critical care settings.

Prescribing information can be found at www.rapiblyk.com

About Rapiblyk®

Rapiblyk® (landiolol) is an ultra-short-acting, selective beta-1 adrenergic receptor blocker indicated for the short-term reduction of ventricular rate in adults with supraventricular tachycardia (SVT) or irregular rapid heart rate, including atrial fibrillation and atrial flutter, especially in perioperative, postoperative, or critical-care settings. Rapiblyk™ provides rapid onset and offset of action, allowing clinicians to achieve precise, controlled rate management with a favorable hemodynamic profile. 

The product is supplied as an intravenous infusion designed for use in a monitored hospital setting.

INDICATION

Rapiblyk® is indicated for the short-term reduction of ventricular rate in adults with supraventricular tachycardia, including atrial fibrillation and atrial flutter.

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

Rapiblyk® is contraindicated in patients with:

• Severe sinus bradycardia, sick sinus syndrome, or >1st-degree AV block
• Decompensated heart failure
• Cardiogenic shock
• Pulmonary hypertension
• Known hypersensitivity to landiolol or formulation components

WARNINGS AND PRECAUTIONS

Includes risk of hypotension, bradycardia, cardiac failure, bronchospasm, masking of hypoglycemia symptoms, infusion site reactions, worsening of Prinzmetal’s angina, complications in pheochromocytoma, peripheral vascular disease, abrupt withdrawal effects, hyperkalemia, metabolic acidosis, and unresponsiveness to epinephrine in hypersensitivity reactions.

ADVERSE REACTIONS

Most important and common adverse reaction is hypotension which in clinical trials occurred in 9.9% of patients receiving Rapiblyk® vs. 1% in those receiving placebo. Please consult the full Prescribing Information for Rapiblyk®: https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/217202s000lbl.pdf 

About AOP Health

AOP Health is a global enterprise with roots in Austria and a mission to address unmet medical needs through innovative, science-driven therapies in cardiovascular and rare disease. Since 1996, the AOP Health Group has been recognized as a pioneer in developing integrated therapy solutions that combine deep scientific expertise with a strong commitment to patient and physician needs. 

Building on this foundation, AOP Health US, LLC was established in 2025 to expand the company’s impact in the United States. The team is focused on introducing its 2024 US FDA approved product for use in the critical care setting, while building the infrastructure to support healthcare professionals and the patients they serve.

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