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Advanced Therapies 

Advanced therapies represent a rapidly evolving area of biomedical innovation that harnesses the potential of genes, cells, or engineered tissues to treat, modify, or cure diseases at their physiological root.

Advanced Therapies are especially relevant for patients suffering from severe, rare, or chronic conditions that do not respond to conventional treatment. As opposed to managing symptoms, these therapies aim to fix the problem at its source—by repairing damaged cells, restoring tissue, or changing how the body responds to disease.

AOP Health's Advanced Therapies is specifically focused on: Somatic Cell Therapy – uses specially prepared living cells to help the body heal, reduce harmful inflammation, or replace damaged tissue. One promising approach within this field uses mesenchymal stromal cells (MSC). These are a special type of stem cell found in various tissues including the skin. Scientists can isolate and multiply these cells to create a therapy that helps calm inflammation and support healing. When given to patients, these cells travel to areas of damage or disease, where they help restore balance and encourage the body’s own healing processes.

DISEASE AREAS:

Epidermolysis Bullosa (EB)
Epidermolysis Bullosa is a rare genetic condition that makes the skin extremely fragile. Even gentle contact can cause painful blisters and open wounds. In more severe forms, the disease also affects the inside of the body, including the mouth and digestive tract. Because the body’s natural healing is impaired, wounds often don’t heal properly and can lead to infections and scarring. Early research shows that a specific type of MSCs may help by reducing inflammation, supporting tissue repair.

Therapy-resistant Chronic Venous Ulcer (CVU) wounds 
Therapy-resistant Chronic Venous Ulcer (CVUs) wounds are long-lasting ulcers that usually appear on the lower legs due to poor blood flow in the veins. These ulcers can be painful, slow to heal, and difficult to treat. Traditional wound care is often not enough. CVU result from increased pressure in the veins, causing fluid and blood cells to leak into the surrounding tissue, leading to skin breakdown and ulcer formation. They are a common complication of chronic venous insufficiency (CVI), a condition where the veins struggle to send blood back to the heart, leading to blood pooling in the lower limbs. 

Insights on Advanced Therapies

Dr. Roland Bindeus

At AOP Health, we care deeply about the daily challenges faced by people living with Epidermolysis Bullosa and therapy-resistant Chronic Venous Ulcer wounds – as well as the families and caregivers who support them. These conditions run deeper than the skin; they profoundly affect quality of life.
We are committed to transforming scientific progress into meaningful outcomes for patients and we believe somatic cell therapy represents a promising and innovative step forward.

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